Product Overview
IGF-1 LR3 (Insulin-Like Growth Factor-1 Long Arg3) is a synthetic analog of human IGF-1 engineered for enhanced metabolic stability and prolonged biological activity. This modified peptide contains a 13-amino acid N-terminal extension and a substitution of arginine at position 3, dramatically reducing its binding affinity for IGF-binding proteins (IGFBPs) while increasing receptor interaction. Our research-grade IGF-1 LR3 offers exceptional purity and consistency, making it a dependable tool for studies involving cellular growth, muscle regeneration, and metabolic signaling.
Must be paired with BAC Water – Typically 1 ml per 1 mg
Key Features
- High Purity: ≥99% purity, verified by third-party laboratory analysis
- Molecular Formula: C₄₀₀H₆₂₅N₁₁₁O₁₂₀S₉
- Molecular Weight: 9117.5 g/mol
- Form: Lyophilized peptide powder for maximum stability and extended shelf life
- Content: 1 mg per vial
Why IGF-1 LR3?
- Enhanced Receptor Affinity: Modified to resist IGF-binding protein interference, allowing prolonged receptor activation.
- Cellular Growth and Repair: Extensively studied for its role in myogenesis, cell differentiation, and tissue regeneration.
- Protein Synthesis Support: Promotes anabolic signaling through the PI3K/Akt/mTOR pathway.
- Metabolic Regulation: Investigated for effects on glucose uptake, lipid metabolism, and insulin sensitivity.
- Extended Half-Life: Longer active duration compared to native IGF-1, making it ideal for in-vitro kinetic and receptor studies.
Applications
This product is intended strictly for laboratory research use only. Common areas of investigation include:
- Cell proliferation and differentiation
- Muscle regeneration and tissue growth models
- Metabolic and insulin signaling pathways
- Aging, recovery, and cellular repair mechanisms
- Studies involving growth factor–mediated anabolic signaling
Important Information
- Supplied as a lyophilized peptide powder
- Store in a cool, dry environment
- Reconstitute with bacteriostatic (BAC) water before use
⚠️ For Research Purposes Only – Not For Human Consumption